Abstract Regulation of global transcription output is important for normal development and disease, but little is known about the mechanisms involved.DNA topoisomerase I (TOP1) is an enzyme well-known for its role in relieving DNA supercoils for enabling transcription.Here, we report a non-enzymatic Rack Accessories function of TOP1 that downregula
There is strong evidence that the implicit biases of health care professionals affect the treatment of patients, and that minority and other Right Handrail marginalized patients are disproportionately harmed.Assumptions made about patient knowledge or lack thereof function as judgments that are prone to bias, which then affect the education and adv
Abstract For neural network potentials (NNPs) to gain widespread use, researchers must be able to trust model outputs.However, the blackbox nature of neural networks and their inherent stochasticity are often deterrents, especially for foundation models Hand Mask trained over broad swaths of chemical space.Uncertainty information provided at the ti